Manu is best known as Icheb on the television series Star Trek: Voyager.

His first name means "First born of a new kind" or "the Law-Giver", while his last name, Intiraymi, is the name of an Incan festival in honor of Inti, the Incan God of the Sun. When he was four years old he saw a production of Peter Pan and this inspired him to become an actor. He was a student at the Howard Fine Studio, gaining experience in both television and theatre.

In 2011, he could be seen in three new feature films; Fortress from Bayou Pictures and Radical 3D, playing the lead role of Charlie O'Hare, Driving By Braille, a new film from WB pictures. He also can be seen in the short films "Expired" and "Ex-girlfriends", making their way around the festival circuit soon. He is also a writer/director.